北京大学神经科学研究所
阅读次数： 发布日期：2018-03-21
教育部神经科学重点实验室和国家卫生计生委神经科学重点实验室与北京大学神经科学研究所与北京大学基础医学院神经生物学系四位一体，同时也是教育部评定的国家级神经生物学重点学科，承担着教学、科研和人才培养的任务。研究所的前身是1993年成立的北京医科大学神经科学中心，同年被评为卫计委（原卫生部）神经科学重点实验室，2001年被评为神经科学教育部重点实验室。
重点实验室自成立以来，紧密围绕国民经济和科技发展的关键问题，定位于应用基础研究，紧密结合和充分发挥实验室的特色，确立了明晰的四个研究方向，包括：(1) 疼痛与镇痛：从外周到中枢的角度，全面阐述急慢性疼痛发生的发生机制。(2) 药物依赖与防治：从病理性学习记忆神经网络的角度，深入探讨毒品与药物成瘾、复吸与消退机制，同时推动临床戒毒研究。(3) 神经系统发育、损伤与重大疾病：围绕神经退行性疾病、神经损伤与修复的细胞分子与病理性记忆的神经网络机制，探讨老年痴呆症高危因素与早期诊断，为临床防治提供新策略。(4) 针刺的神经生物学机制：继承实验室针刺现代研究的传统，深入探讨针刺治疗慢性疼痛的作用及其调控中枢网络的机制。
目前，固定人员41人，其中教授16人，研究员3人，特聘研究员5人，副教授4人，副研究员3人，讲师3人，高级职称技术人员2人，中级职称技术人员5人。其中，院士2人、教育部长江学者特聘教授2人、国家杰出青年基金获得者3人，中组部千人计划专家1人，青年千人专家1人，优秀青年基金获得者1人，中组部万人计划青年拔尖人才1人。
近年来，实验室成员的研究成果多次获得家科学技术进步奖，高等学校科学研究优秀成果奖，北京市科学技术进步奖等诸多奖项。韩济生教授获得中国医学最高奖—吴阶平医学奖，获得国际疼痛学会荣誉会员，成为目前唯一入选的中国学者。
实验室的所有四个研究方向都获得了“973计划”，“国家自然科学基金重点项目/面上项目”的资助。实验室在国家及北京大学经费的资助下，建设了神经科学研究平台，开展了多项本学科领域的前沿技术，有力支撑了北京大学医学部的神经科学研究。目前实验室面积近5000平米，包括动物行为实验室、细胞实验室、显微成像平台、分子生物学实验室、形态学实验室、在体及脑片膜片钳电生理实验室、脑电多通道实验室等多个平台。实验室仪器设备总计近2000台件，价值3600余万元。实验室大型贵重设备均纳入公用设备平台由专人管理，采用网络预约的方式使用。
近年来，重点实验室成员所发表的SCI论文刊登在Nature Communications, Journal of Clinical Investigation,Biological Psychiatry,Neuropsychopharmacology, The Journal of Neuroscience, Pain, Glia, Addiction Biology等本专业领域的顶尖杂志中，并多次得到编辑部评述、专业网站评论，研究成果被编写入国际教科书，并多次荣获国家科学技术进步奖等。
实验室是中华医学会疼痛学分会、中国医师学会疼痛医师分会和北京神经科学会的创始与挂靠单位，引领和推动了国内疼痛医学学科的建科与发展，连续两次作为首席科学家单位组织疼痛与针刺的“973项目”。实验室受国际标准组织邀请，制定电针仪ISO国际标准，占据了电针仪产业化的国际制高点。
机构负责人：万有 ywan@hsc.pku.edu.cn 010-82805185
联系人：李亦婧 liyijing@bjmu.edu.cn 010-82805526
地址：北京市海淀区学院路38号，100083
网址链接：http://neurokeylab.bjmu.edu.cn/
Key Lab for Neuroscience, The Ministry of Education of China
Key Lab for Neuroscience, The National Health and Family Planning Commission of China
Key Laboratory for Neuroscience of Ministry of Education, and Key Laboratory for Neuroscience of National Health and Family Planning Commission composes Department of Neurobiology, School of Basic Sciences, Peking University, Neuroscience Research Institute of Peking University, and National Key Discipline of Neuroscience. It is responsible for not only neuroscience research, but also undergraduate and graduate teaching in Peking University. The history of the Key Lab dates back to 1993, when Neuroscience Research Center, Beijing Medical University (predecessor of Peking University Health Science Center) was founded. It was awarded as Key Laboratories for Neuroscience of National Health and Family Planning Commission in 1993, as well as Key Laboratories for Neuroscience of Ministry of Education in 2001.
The Key Lab performs bench and bedside research and focuses on both modern sciences and traditional Chinese medicine. The major research directions of the Key lab include:
- Pain and analgesia
- Drug addiction and its treatment
- Neural development, nerve injury and critical diseases
- Neurobiological mechanisms of acupuncture
Currently there are 41 members in the Key Lab, including 16 professors, 8 investigators, 4 associate professors, 3 associate investigators, 3 lecturer and 7 technicians. Among them, there are 2 Members of Chinese Academy of Sciences, 2 Chang Jiang Scholars, 3 recipients of the National Science Foundation of China for Distinguished Young Scholars, 1 specialist of One Thousand Talents Program, 1 specialist of One Thousand Young Talents Program, 1 recipient of the National Science Foundation of China for ExcellentYoung Scholars.
Faculty members of the Key Lab have won several honors and awards at national and international levels, including the National Award of Science and Technology Progress,Science Research Famous Achievement Award in Higher Institution, Beijing Science and Technology Progress Award etc. Professor Han has won the WU Jie-Ping Medical Award, Honorary Member of International Association for the Study of Pain.
Researches in the Key Lab have been supported by the National Basic Research Program of China (“973” Program) by the Ministry of Science and Technology, National Natural Science Foundation of China and other national-level foundations.
The facility platform in the Key Lab is funded by government and Peking University. It plays a key role in supporting neuroscience research within the Peking University Health Science Center. The facility platform consists of Behavioral laboratory, Cell culture laboratory, Microscopy imaging laboratory, Molecular biology laboratory, Morphologylaboratory, Electrophysiological laboratory, etc. The platform is run by full-time staff and provides support for researchers from within the Key Lab as well as from outside.
Research papers mainly published in international journals including top journals in the field like Nature Communications, Journal of Clinical Investigation,Biological Psychiatry,Neuropsychopharmacology, The Journal of Neuroscience, Pain, Glia, Addiction Biology. Some publications have been published with editorial, compiled into international textbook and won many national science and technology progress awards.
The Key Lab is also the founder of Chinese Association for the Study of Pain (CASP), Pain Physician Branch of Chinese Medical Doctor Association, Beijing Neuroscience Society. The Lab also set International Standardization Organization standard for electroacupuncture devices.
Director: Prof. Wan You, ywan@hsc.pku.edu.cn 010-82805185
Contact: Dr. Yijing Li,liyijing@bjmu.edu.cn 010-82805526
Address: 38 Xueyuan Road, Haidian District, Beijing, 100083, P. R. China.
Website: http://neurokeylab.bjmu.edu.cn/