“女性盆底疾病研究北京市重点实验室”是女性盆底疾病研究的创新平台，依托北京大学人民医院，研究女性盆底功能障碍性疾病的病因、个体化评估方法和用于诊疗的新型材料。北大人民医院盆底疾病研究已有十余年历史：2002年即率先在我国开展了女性盆底疾病的诊治；2011年成立盆底疾病诊治中心；2015年在女性盆底疾病防治方面获得两项成果奖；2016年12月，获批“女性盆底疾病研究北京市重点实验室”；2017年成立中国妇女盆底功能障碍防治项目质量控制中心；2017年成立北京大学医学部女性盆底疾病研究中心。

　　研究领域：主要研究女性盆底障碍性疾病，包括盆腔器官脱垂、下尿路症状、肠道功能障碍、会阴区疼痛、性生活障碍等。从疾病诱因、发病机制、评估方法、个体化治疗等多方面进行研究，汇集了妇产科、泌尿外科、胃肠外科、消化内科、疼痛科、精神心理科、磁共振成像中心、材料化学及组织工程力学等多个临床、基础学科。

　　主要研究方向：①病因学研究；②利用磁共振功能成像，结合组织工程力学研究，旨在发现女性盆底疾病的发病机制及个体化病情评估，为精准治疗提供基础。③研发自主知识产权盆底组织工程补片，弥补了国内此领域的空白，旨在解决现有补片价格昂贵、并发症多的难题。盆底补片制备方法已获批国家发明专利。

　　“北京市女性盆底疾病研究重点实验室”承担盆底疾病基础研究工作，有专职的实验人员和研究生从事科研工作。技术队伍实力雄厚，实验室拥有博士生导师6人，研究员2人，学术委员会成员13人；实验室设施齐全，布局合理，科研气氛浓厚。

　　实验室利用材料化学、工程组织力学、3D成像技术等多学科交叉融合，研发具有自主知识产权的组织工程盆底补片、探讨盆底疾病的发病机制等。

　　奖项：

　　2015年“女性盆底功能障碍疾病病情综合评估及多学科诊疗模式的建立与应用”获高等学校科学研究优秀成果奖二等奖

　　2015年“基于功能重建的女性生殖道整形基础与临床研究”获中国整形美容协会科学技术奖创新奖

　　2015年王建六教授荣膺“科学中国人年度人物”。

　　2017年获中华预防医学会颁发的中国妇女盆底障碍防治项目“先进集体奖”，王建六教授荣获“突出贡献奖”，杨欣教授、孙秀丽教授荣获“优秀个人奖”，安方医师荣获“优秀论文奖”

　　先后获得卫生部临床重点项目、首发基金重点项目以及教育部新教师基金、北京大学前沿交叉课题、北京大学“985工程”三期临床医院合作专项、中华预防医学会专项基金、北京市科委重大研究项目、国家自然科学基金等基金支持，近3年出版论著13本，发表相关论文50余篇，获科技成果奖3项、发明专利成果1项。

　　经过多年的临床、科学研究，发展了女性盆底疾病多学科的诊治模式和个体化的疾病评估及预测模型，显著提高手术后成功率，并降低手术并发症，节约了医疗资源，提升了医疗质量。研发的具有自主知识产权的新型组织工程补片有望应用于临床。

　　

 

　　机构负责人：王建六

　　联系人：孙秀丽

　　邮箱：pkuhsc_pelvicfloor@163.com

　　电话：01088324385

　　地址：北京市西城区西直门南大街11号

　　

　　Beijing Key Laboratory of Female Pelvic Floor Disorders

　　As an innovative platform of female pelvic floor disorders research, the Beijing Key Laboratory of Female Pelvic Floor Disorders is initiated by the Peking University People’s Hospital, focusing on the pathogenesis, individualized evaluation method and new treatment materials of female pelvic floor disorders. The research on pelvic floor disorders has a history of over 10 years in the Peking University People's Hospital. In 2002, the Peking University People’s Hospital was the first to carry out the diagnosis and treatment of female pelvic disorders in China; in 2011, the Center for Pelvic Floor Disorders was established; in 2015, the Peking University People’s Hospital won two achievement awards in the prophylaxis of female pelvic floor disorders; in December 2016, the Beijing Key Laboratory of Female Pelvic Floor Disorders was established; in 2017, the Chinese Female Pelvic Floor Disorders Control Project Quality Control Center was established; and also in 2017, the Peking University Health Science Center Female Pelvic Floor Disorders Research Center was established.

　　Research interests: mainly focus on female pelvic floor disorders, including pelvic organ prolapse, lower urinary tract symptoms, intestinal dysfunction, perineal pain, sexual dysfunction and so on. We have studied in multiple aspects such as risk factors, pathogenesis, evaluation methods, and individualized treatment. Meanwhile, we have integrated multiple clinical and basic disciplines, including gynecology, urology, gastrointestinal surgery, gastroenterology, pain management, psychiatry & psychology, magnetic resonance imaging center, materials chemistry, and tissue engineering.

　　Main research directions: 1. Etiological research; 2. Together with MRI and tissue engineering researches, we are dedicated in investigating the pathogenesis of female pelvic floor disorders and the individualized disease evaluation, so as to provide the foundation for precision medicine; 3. We have developed our own intellectual property right of a pelvic floor tissue engineering mesh which makes up the domestic blank. It aims to solve the problems of costs and complications caused by the current meshes. The manufacturing method of this pelvic floor mesh has obtained the national invention patent.

　　Undertaking the basic study on pelvic floor disorders, the Beijing Key Laboratory of Female Pelvic Floor Disorders has full-time laboratory staff and graduated students to engage in the scientific research. We have a powerful technical team, including 6 doctoral advisors, 2 researchers, and 13 academic committee members. We have well-equipped laboratories with reasonable lay-out and strong scientific research atmosphere.

　　Taking the cross-merging advantages of multi-disciplines such as material chemistry, tissue engineering, and 3D imaging, our laboratory has developed our own intellectual property right of a pelvic floor tissue engineering mesh and has explored the pathogenesis of pelvic floor disorders.

　　Awards:

　　2015    Comprehensive evaluation and multidisciplinary diagnosis and treatment of female pelvic floor dysfunction and its application, Science Research Famous Achievement Award in Higher Institution, Second Prize

　　2015  The experimental and clinical studies of female genital organ plasty based on the functional reconstruction, Chinese Association of Plastics and Aesthetics, Science and Technology Award, Innovation Award

　　2015    Professor Wang Jianliu won the title of Scientific Chinese “People of the Year”.

　　2017   The Chinese Female Pelvic Dysfunction Control Project, Chinese Preventive Medicine Association, Advanced Unit Award; Professor Wang Jianliu won the Outstanding Contribution Award; Professor Yang Xin and Professor Sun Xiuli won the Outstanding Individual Award; Physician An Fang won the Outstanding Paper Award.

　　Achievements and Contributions:

　　We are supported by the National Health and Family Planning Commission of the People’s Republic of China Key Clinical Project, Capital Foundation of Medical Developments Key Project, Specialized Research Fund for the Doctoral Program of Higher Education, Peking University Advanced Interdisciplinary Research Project, Peking University Project 985 Phase III Clinical Hospital Cooperation Special Project, Chinese Preventive Medicine Association Special Fund, Beijing Municipal Science & Technology Commission Major Research Project, National Natural Science Foundation and so on. In the past three years, we have published 13 books and more than 50 relevant papers; meanwhile, we have achieved 3 Technology Achievement Awards and one invention patent.

　　Through years of clinical and scientific researches, we have developed the multidisciplinary diagnosis and treatment model of female pelvic disorders and the individualized disease evaluation and prediction model, which significantly improved the post-operative success rate, reduced operative complications, saved medical resources, and improved the quality of medical care. A new type of tissue engineering mesh with our own intellectual property right is expected to be used in the clinical practice.

　　Director: Wang Jianliu

　　Contact Person: Sun Xiuli

　　Email: pkuhsc_pelvicfloor@163.com

　　Phone: (+86) 1088324385

　　Address: No. 11 Xizhimen South Street, Xicheng District, Beijing, China