依托北京大学肿瘤医院建设的上消化道肿瘤北京市国际科技合作基地，于2019年被北京市科学技术委员会认定为2018年度北京市国际科技合作基地，基地负责人季加孚教授。

　　基地建设总体目标是建立新型上消化道肿瘤高危人群识别技术，有效提高上消化道肿瘤检出率及早诊率；寻找预警、早诊及疗效预测标志物，并进行相关功能研究；研发新型靶向药物，建立上消化道肿瘤早诊及精准治疗模式。管理模式是以中外双方共同成立科学委员会及管理委员会，联合申报和启动科研项目，风险利益共担，建成共建共管的新型国际合作平台。主要合作方式是针对我国特有的高发瘤种，借鉴欧美国家先进的研究技术平台，开展以我国科学家为主导的上消化道肿瘤国际合作研究。通过深入探索，有机结合，促进成果快速转化，全面提升我国胃癌、食管癌等的综合诊治水平，造福患者。

　　基地拥有“恶性肿瘤发病机制及转化研究”教育部及北京市重点实验室，汇聚一支整体研究实力和国际学术竞争能力较强的专门科研队伍，有多名在国际上具学术影响力的学科带头人，例如基地负责人季加孚教授担任国际胃癌学会主席，游伟程教授和潘凯枫教授任国际胃癌学会常务委员和委员等。

　　目前，基地已有中-德，中-英，中-美三个持续性国际战略合作平台。与德国慕尼黑大学开展长期合作，2017年获得德国联邦教育与研究部（BMBF）批准，建立了中-德上消化道肿瘤联合重点实验室，这是BMBF批准的8个中德联合项目中唯一生物医学领域的联合重点实验室。在此基础上与北京大学医学部联合申报科技部国际科技合作基地并获得批准。与英国卡迪夫大学长期合作，中英双方基于培养临床基础复合型人才为目标而共同创建了联合研究所。与美国霍普金斯大学合作，建立了中-美肿瘤免疫治疗联合研究实验室，共同致力于胃癌免疫综合治疗的探索。

　　基地的建设不仅符合全国科技创新中心建设的发展目标和北京科技创新的重点方向和任务，更重要的是这种新型国际合作模式将发挥积极的引领和示范的作用，对全面提升我国上消化道肿瘤的防治水平具有重要的支撑作用。

　　

　　基地负责人：季加孚

　　联系人：贾淑芹

　　邮箱：kjc126@163.con

　　电话：88196926

　　地址：北京市海淀区阜成路52号

　　

　　Beijing International Science and Technology Cooperation Base for Upper Gastrointestinal Cancers

　　The international cooperation platform for upper gastrointestinal (GI) cancers established at Peking University Cancer Hospital (PKUCH) was certified by Beijing Municipal Science and Technology Commission as a 2018 Beijing International Cooperation Base (hereinafter referred to as “the Base”). The Base is headed by Prof. Jiafu JI.

　　The overarching goals of the Base are: to develop new high-risk population identification technology for upper GI cancers,and improve the detection rate and early diagnosis rate of upper GI cancers; to identify early diagnosis and predictive biomarkers, and study the function of related markers; to conduct basic and clinical research into new targeted drugs, and to establish an effective model for upper GI cancer detection and precision treatment. It is a novelinternational cooperation platform co-founded and co-managed by a Scientific Committee and a Management Committee jointly established by PKUCH and its international partners who will work together to apply for and implement research projects and share risks and benefits. The main cooperation model of the Base is to take advantage of advanced international research technology and conduct cooperative studies on high-incidence cancers of Chinaled by Chinese scientists. The Base is also engaged in translation of research findings into clinical practices, so as to improve diagnosis and treatment of gastric and esophageal cancers and benefit the patient in China.

　　The Base has a Key Laboratory of “Carcinogenesis and Translational Research” certified by Ministry of Education and Beijing Municipal Science and Technology Commission, and a internationally recognized dedicated research team of academic competitiveness, several of whom are world-renown leaders in their respective fields. For example, Prof. Jiafu JI was appointed president of International Gastric Cancer Association (IGCA) between 2017 and 2019, Prof. Weicheng YOU and Prof. Kaifeng PAN hold membership of IGCA.

　　At present, the Base has set up three international strategic cooperation platforms. In 2018, under approval and support of German Federal Ministry of Education and Research (BMBF), the Base and its long-term partner Technical University of Munich established a Joint Key Laboratory for upper GI cancers. This is the only one of the eight Sino-Germany collaborative programs approved by BMBF that is specialized in biomedicine. Based on this program, the Base and PKUCH jointly applied for and approved as the International Science and Technology Cooperation Base of the Ministry of Science and Technology, P. R. China. The Base has established a Joint Institute with Cardiff University, UK, working toward the goal of cultivating all-around talents good at both clinical practices and research. The Base has also launched the Sino-US Joint Laboratory for cancer immunotherapy committed to exploration of comprehensive immunotherapy for gastric cancer.

　　The base is in line with the development goals of the National Science and Technology Innovation Center and the key missions of Beijing's scientific and technological innovation. More importantly, this new type of international cooperation model sets a valuable example and provides useful guidance for future cooperation,  which will significantly promote improvement of upper GI cancer prevention and treatment in China.

　　

　　Director of the Base: Jiafu JI

　　Contact: Shuqin JIA

　　Email: kjc126@163.con

　　Tel: 88196926

　　Add: 52 Fucheng Rd., Haidian District, Beijing 100142